ChemicalBook > CAS DataBase List > 1-Boc-Azetidine-3-yl-methanol

1-Boc-Azetidine-3-yl-methanol

Product Name
1-Boc-Azetidine-3-yl-methanol
CAS No.
142253-56-3
Chemical Name
1-Boc-Azetidine-3-yl-methanol
Synonyms
TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE;EOS-61767;Boc-Azetidin-3-ylMethanol;1-Boc-3-(hydroxymethyl)az...;1-BOC-AZETIDINE-3-YL METHANOL;1-Boc-3-azetidinemethanol,95%;1-Boc-3-azetidineMethanol, 95%;1-N-Boc-3-hydroxyMethyazetidine;1-Boc-3-(hydroxymethyl)azetidine;1-Boc-3-(hydroxyMethyl)azetidine, 97+%
CBNumber
CB8246260
Molecular Formula
C9H17NO3
Formula Weight
187.24
MOL File
142253-56-3.mol
More
Less

1-Boc-Azetidine-3-yl-methanol Property

Melting point:
55 °C
Boiling point:
268-273℃
Density 
1.115
Flash point:
117°(243°F)
storage temp. 
2-8°C
solubility 
Soluble in Dimethyl sulfoxide (DMSO).
pka
14.82±0.10(Predicted)
form 
powder to lump
color 
White to Almost white
InChI
InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3
InChIKey
HXRDRJKAEYHOBB-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CC(CO)C1
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-26-37-60
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B3992
Product name
1-(tert-Butoxycarbonyl)-3-azetidinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$121
Updated
2024/03/01
Alfa Aesar
Product number
H57112
Product name
1-Boc-3-azetidinemethanol, 95%
Packaging
500mg
Price
$127
Updated
2023/06/20
Alfa Aesar
Product number
H57112
Product name
1-Boc-3-azetidinemethanol, 95%
Packaging
250mg
Price
$68.2
Updated
2021/12/16
TRC
Product number
B750283
Product name
tert-butyl3-(acetoxymethyl)azetidine-1-carboxylate
Packaging
2.5g
Price
$130
Updated
2021/12/16
Usbiological
Product number
261930
Product name
1-Boc-azetidine-3-yl-methanol
Packaging
50g
Price
$1018
Updated
2021/12/16
More
Less

1-Boc-Azetidine-3-yl-methanol Chemical Properties,Usage,Production

Description

1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Chemical Properties

Clear colorless liquid

Uses

It is an intermediate in organic syntheses

1-Boc-Azetidine-3-yl-methanol Preparation Products And Raw materials

Raw materials

Acetonitrile Toluene Di-tert-butyl dicarbonate Benzylamine Formaldehyde N,N-Diisopropylethylamine Sodium borohydride Palladium Boron trifluoride diethyl etherate Tetrahydrofuran Trifluoroacetic anhydride Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Diethyl malonate Thionyl chloride Ammonia

Preparation Products

More
Less

1-Boc-Azetidine-3-yl-methanol Suppliers

Americas 1 Belgium 2 Canada 2 China 203 Europe 1 France 1 Germany 2 India 5 Japan 2 South Korea 1 The Netherlands 1 United Kingdom 7 United States 34 Global 262
More
Less

View Lastest Price from 1-Boc-Azetidine-3-yl-methanol manufacturers

Anhui Ruihan Technology Co., Ltd
Product
1-Boc-azetidine-3-yl-methanol 142253-56-3
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-08
Career Henan Chemical Co
Product
1-Boc-azetidine-3-ylmethanol 142253-56-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-23

142253-56-3, 1-Boc-Azetidine-3-yl-methanolRelated Search:

Buprofezin tert-Butanol Diethylene glycol monobutyl ether n-Butane 1-Bromobutane 1-Chloro-2-methylpropane Tris(hydroxymethyl)nitromethane Butyl acetate RESMETHRIN Cyhalofop-butyl Butyl acrylate 1,2,3,4-Butanetetracarboxylic acid tert-Butyl acetate tert-Butyl peroxyacetate ISOBUTANE tert-Butyl 4-broMo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate tert-butyl 3-broMo-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (R)-1-Boc-2-cyanopyrrolidine

  • 1-Boc-3-azetidineMethanol, 95%
  • Boc-Azetidin-3-ylMethanol
  • 1-(tert-Butoxycarbonyl)-3-azetidineMethanol
  • 1-Azetidinecarboxylic acid, 3-(hydroxyMethyl)-, 1,1-diMethylethyl ester
  • EOS-61767
  • 1-Boc-3-(hydroxyMethyl)azetidine, 97+%
  • TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE
  • 3-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 1-BOC-AZETIDINE-3-YL METHANOL
  • 3-(Hydroxymethyl)azetidine-1-carboxylate
  • 1-Boc-3-(hydroxymethyl)azetidine
  • 1-Boc-3-(hydroxymethyl)az...
  • 1-N-Boc-3-hydroxyMethyazetidine
  • tert-butyl 2-(azetidin-3-yl)-2-hydroxyacetate
  • 1-(tert-Butoxycarbonyl)-3-azetidinemethanol &gt
  • 1-Boc-3-azetidinemethanol,95%
  • 1-tert-Butoxycarbonyl-3-hydroxymethylazetidine
  • 142253-56-3